Toxins, environmental pollution and inflammation

Precision medicine and apheresis - a new approach to modern therapy

The medicine of the future is personalized, precise and holistic. One of the most promising approaches in this new era is apheresis therapy, which specifically removes unwanted substances from the blood to treat inflammation, lipid disorders and even chronic infections.
In the following, we take a look at the latest scientific findings that shed light on the potential of apheresis in various medical fields.

1. lipoprotein apheresis - more than just lipid reduction

Lipoprotein apheresis (LA) has established itself as a highly effective therapy for the treatment of familial hypercholesterolemia and lipoprotein(a) hyperlipidemia.

Despite its invasive nature, it shows

• High effectiveness in lipid reduction
• Minimal side effects
  
• Demonstrable reduction in cardiovascular events
  
  

"Can apheresis do more than just lower cholesterol?"

In fact, studies indicate that the effectiveness of LA goes beyond pure lipid reduction. It also removes proinflammatory and proatherogenic factors, leading to a more comprehensive cardiovascular risk reduction.

2. microplastics - invisible danger to health and the environment

Plastic pollution is no longer a purely ecological problem. Microplastics have become a serious threat to food systems and human health.

"How much does microplastic affect our blood, our cells - and ultimately our well-being?"

Studies show:

• Microplastics are created when plastics break down into tiny particles
  
• These particles end up in drinking water and food
  
• They can release toxic chemicals that:
  
  • Promote inflammation
  • Trigger genotoxicity and carcinogenicity
  • Cause neurological and cardiovascular damage

The findings on nanoplastics (NPs) are particularly alarming - they indicate chronic toxicity affecting the liver, heart and nervous system.

3. lipid profiles in Lyme borreliosis - a possible role for apheresis

Lyme borreliosis, caused by Borrelia burgdorferi, is a complex bacterial infection that causes a variety of symptoms. The latest research indicates a close link between lipid metabolism and the course of the disease.

Research results show:

• Borrelia use host lipids for their survival
• Patients with Lyme disease show altered lipid profiles
  
• Elevated lipid levels can increase the severity of the disease
  
  

These findings lead to an exciting hypothesis:
Apheresis could help to influenceinflammatory processes and bacterial persistence through lipid reduction. Initial pilot trials support this innovative approach - further research is underway.

4. post-COVID-19 and chronic fatigue syndrome - hope through extracorporeal apheresis

Many patients struggle with persistent symptoms after a SARS-CoV-2 infection - known as post-COVID or long-COVID. These include:

• Chronic fatigue
• Shortness of breath
• Cognitive impairment

This symptomatology is very similar to chronic fatigue syndrome (CFS).

"What if the solution to fatigue lies in the blood itself?"

Current studies show increased autoantibodies against neurotransmitter receptors in Long COVID and CFS patients.
Extracorporeal apheresis offers a new approach here:

• It reduces autoantibody concentrations in the blood
• Can alleviate symptoms such as fatigue and concentration disorders
• Opens up avenues for new therapeutic strategies

5. particles in the eluate of double filtration plasmapheresis - science in detail

Double filtration plasmapheresis (DFPP) is an advanced blood purification procedure associated with INUSpheresis® technology.

A recent study investigated which micro- and nanoparticles remain in the eluate after treatment.

"What remains after the blood has been purified?"

Field emission scanning electron microscopy (FE-SEM-EDX) was used to identify particles that:

• Contain high concentrations of calcium, iron, silicon, aluminum and titanium
• Potentially allow conclusions to be drawn about exogenous or endogenous contamination
• Are relevant for environmental medical diagnostics
  
  

These findings emphasize that DFPP technology can be valuable not only therapeutically but also diagnostically.

6 INUSpheresis® for chronic inflammation - an innovative approach

Chronic inflammation is considered to be the silent driver of numerous diseases - from autoimmune diseases to neurodegenerative processes.

"Can we stop inflammation before it becomes a disease?"

This is where INUSpheresis® therapy comes in:

• Reducing inflammatory mediators, toxins and oxidative stress
• Regulating the immune system
• Stabilizing the cell metabolism

Typical indications for INUSpheresis®:

• Alzheimer's disease
• Lyme disease
• Chronic fatigue syndrome (CFS)
• Hashimoto's thyroiditis
• Leaky gut syndrome
• Mitochondrial diseases
• Nitrostress and oxidative stress

The studies presented here clearly show that apheresis is more than just a classic detoxification:

It is a precise, science-based approach that harmonizes metabolism, immune system and cellular health.

With procedures such as INUSpheresis®, medicine is becoming increasingly individualized - with the aim of treating diseases holistically before they become chronic.

"Precision medicine begins where therapy is tailored to the biochemistry of the individual."